A study on the propolis produced in the south of Portugal has confirmed its effectiveness as an anti bacterial, and disclose that the product collected in the spring shows a greater effectiveness on some strains produce gastrointestinal disease.
The propolis -resinous substance naturally produced by honeybees Apis mellifera L – exists in natural form, and can be consumed as such, as a medicine. The research however compared the sensitivity of bacteria against extracts collected in the environment of ethanol, methanol, and the type water, in support of the pharmaceutical production, and its introduction into the cosmetic or food industry.
The results confirmed that propolis extracted and diluted effectively has bactericidal effect, “but its sensitivity depends on the dose”, indicates the document.
What is interesting is that two samples of propolis collected in the spring showed higher antibacterial activity, compared to samples harvested in winter”. The bacterial strains Helicobacter pylori J99 and 26695were the most susceptible, and these are demonstrated both in the samples etanólicas as metanólicas.
The following is a table of the results of the samples of propolis of winter, with extracts of ethanol, methanol, and the type aqueous:
The results of the samples of propolis of winter, with extracos of ethanol, methanol, and the type aqueous:
As you can compare between the two tables, the action inhibitora on the bacteria, the propolis from the spring, is larger, especially in extracts of ethanol and methanol.
“This study constitutes the first approach of the biological activities of propolis Portuguese region of the Algarve and is evidence of its potential to combat bacterial infections. In particular against the pathogen of gastric H. pylori, the results are promising for the monitoring of the use of propolis to combat this important gastrointestinal disease”, highlighted the team of researchers, led by Ana Vanessa Oliveira, of the University of Santiago de Compostela and Ana Luisa Ferreira, University of Algarve.
The analysis found that in winter, the concentrations of phenols, total flavone, flavonols, flavanones and dihidroflavonoles were different, depending on the place, as well as the type of solvent used. For example, when we used 70% ethanol as extraction solvent of propolis, the sample had the highest amounts of flavanones and dihidroflavonoles, which extracts aqueous.
Flavonoids, present in the vegetables, give the body protection against the oxidizing effects such as environmental pollution, ultraviolet rays, and the extremely harmful substances that are found in food.
According to the researchers, the water is demonstrated as the solvent poorer for the extracting phenols and flavonoids in all samples of propolis.
The document quotes several studies that have shown in the past that the propolis has a chemical composition very complex, which depends on the local flora and, therefore, of the geographical and climatic conditions of the site. By the diversity of this chemical composition, is attributed to a wide range of biological activities: antibacterial, anti-inflammatory, antioxidant as well as hepatoprotective effects and anti-tumor. Therefore, the presence of antioxidant compounds and phenolics, such as flavonoids and phenolic acids, are of therapeutic interest.
On the other hand reports that in the scientific community have been recognized, the Pinocembrina and pinostrombina how agents flavonoids are effective against bacteria, but also the ferulic acid and caffeic acid from propolis have a strong bactericidal action.
The caffeic acid followed by the taxifolin predominated in all samples of propolis Portuguese, both in the winter, how in the spring, in ethanolic extracts and methanolic. Exhibited antimicrobial activities similar to each other and superior to those obtained with aqueous extracts.
The remarkable thing about the research is that the antimicrobial activity although, in general, was similar in the propolis winter and spring, in the propolis of spring demonstrates the great effectiveness against the bacteria causing gastrointestinal diseases, such as Helicobacter pylori J99 and Salmonella Thyphimurium.
Eating propolis can be a good effective remedy in some cases.
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